Stem cell therapy works to tap into regenerative abilities to help repair damaged tissues potentially. Doctors obtain stem cells from varied human tissues using techniques such as bone marrow aspiration and umbilical cord collection. Under clinical protocols, these cells receive laboratory concentration and processing. Here is an overview of the steps involved in a stem cell procedure:
Exploring Types of Stem Cells
Doctors categorize stem cells based on their source. Autologous stem cells come from the patient and are derived from bone marrow or adipose tissue. Allogeneic stem cells come from donor sources like umbilical cord blood. Induced pluripotent stem cells (iPSCs) are lab-created by reprogramming adult cells into those with embryonic capabilities. Researchers aim to enhance the safety, efficiency, and scalability of iPSC production methods to make stem cell therapies more accessible. Embryonic stem cells come from embryos and carry specific regulations.
Preparing for Cell Harvesting
In the early stages, evaluation helps doctors determine whether you qualify for stem cell therapy. Initial tests and imaging map the targets for the cellular administration. Diagnostic assessments reveal any factors excluding eligibility, such as severe autoimmune diseases. A comprehensive review of the patient’s medical history helps identify conditions that may influence the effectiveness or safety of stem cell procedures.
Exploring Patient Evaluation Steps
Evaluation of diagnosis, medical history, and lifestyle factors reveals whether stem cells will help achieve a patient’s care goals. Conditions like psoriasis and multiple sclerosis are still considered unsuitable under current guidelines. Patients with these immune-mediated conditions may not respond optimally to stem cell procedures.
Discovering Stem Cell Sources
Once a patient is approved, doctors determine the source of cells that their immune system will not reject. Some patients can use their biological material through autologous donations. Bone marrow contains concentrated and viable types of stem cells for regenerative therapy. Factors such as systemic diseases and pre-existing health conditions in donors can reduce the quality and viability of harvested stem cells. For those unable to use their materials, allogeneic stem cells present an alternative through younger, viable materials.
Harvesting Stem Cells
The harvesting and isolation of stem cells occur in certified tissue banks. Donor parents sign consent forms allowing umbilical cord blood collection at birth. The cord is first clamped and cut, with blood then extracted from the umbilical vein. Collected samples are transported in specialized containers to the laboratory quickly, ensuring the cells remain viable and uncontaminated. Tools like ultrasound imaging guide bone marrow extraction from donor sites like the hipbone, maximizing yields of regenerative cells.
Processing Stem Cells
Laboratory technicians place raw stem cell material into systems replicating the body’s conditions. Stem cells are cultured in growth media containing nutrients and compounds to support their development. While under proprietary patent protection, pharmaceutical-grade cytokines get integrated in stages. Ongoing monitoring allows the technician to adjust inputs and other variables.
Discover Stem Cell Therapy
Ongoing clinical research and patient trials continue to find new uses for this procedure and further refine the capability of stem cell therapy. Speak to a specialist about how stem cell procedures will be tailored to your diagnosis and health needs. A therapy plan for a patient will maximize regenerative treatment with minimal risks. Discuss strategies with a qualified specialist to explore the benefits that may be possible from a stem cell procedure.
